What allergy medicine was taken off the market?
WASHINGTON (CNN) — Federal regulators are moving to take a popular allergy medicine, Seldane, off store shelves after findings that it can cause a potentially fatal heart condition when combined with certain other drugs..
What is hismanal used for?
Hismanal (astemizole) is an antihistamine used to treat allergies, hives (urticaria), and other allergic inflammatory conditions.
What replaced Seldane?
On Monday, the FDA announced it had approved another formulation of Allegra–Allegra-D, which adds a decongestant to the non-sedating antihistamine–enabling the company to market two versions of Allegra, as it had with Seldane.
Which are the best antihistamines?
Claritin and Zyrtec are popular over-the-counter antihistamines. Doctors consider them safe and effective treatments for minor allergies. Both are second-generation antihistamines. These cause less drowsiness than first-generation antihistamines.
Why was terfenadine removed from the market?
Terfenadine was taken off the market due to the risk of cardiac arrhythmia caused by QT prolongation. The active metabolite is not cardiotoxic, however, and is now sold under the brand name Allegra.
Why was hismanal withdrawn?
Last year the US Food and Drug Administration warned that astemizole—marketed under the brand name Hismanal—could cause fatal arrhythmias when given in high doses or in combination with certain other common drugs.