Quick Answer: When Should I Be Concerned About High Platelet Count?

Can stress cause high platelets?

Stressful life events and anxiety usually cause an increase in platelet volume and activity through various mechanisms.

Mean platelet volume (MPV), which is indicative of platelet size, is accepted as an indication of platelet activity..

What is high platelet count called?

When another disease or condition causes a high platelet count, the term “thrombocytosis” is preferred. This condition often is called secondary or reactive thrombocytosis. Secondary thrombocytosis is more common than primary thrombocythemia. Often, a high platelet count doesn’t cause signs or symptoms.

Do high platelets always mean cancer?

If a person’s platelet count remains high, the following medical conditions may be responsible: Cancer: Lung, stomach, breast, and ovarian cancers, as well as lymphoma, can cause high platelet counts. Additional blood testing, imaging scans, or a biopsy can test for cancer.

What cancers cause a high platelet count?

Of 68,181 male patients with levels of blood platelet on the higher end of normal, 1,869 cases of cancer were diagnosed within one year. Of these, 720 were an advanced stage. A higher platelet count was most frequently linked to lung and colorectal cancers—both aggressive forms of cancer.

Can bacterial infection cause high platelet count?

Any inflammatory process such as bacterial infection, neoplasia, sepsis, multiple trauma, burns, or pancreatitis that elevates serum IL levels (especially IL-6), may increase the circulating platelet count (2,3).

What does a high platelet count indicate?

A high platelet count may be referred to as thrombocytosis. This is usually the result of an existing condition (also called secondary or reactive thrombocytosis), such as: Cancer, most commonly lung cancer, gastrointestinal cancer, ovarian cancer, breast cancer, or lymphoma.

How do I bring my platelets down?

Your doctor may suggest one of the following prescription drugs, perhaps along with low-dose aspirin, to reduce your platelet count or clotting risk: Hydroxyurea (Droxia, Hydrea). This drug suppresses bone marrow production of blood cells, including platelets.

Is 450 a high platelet count?

Your haematologist will check your platelet count in particular. Platelets are the cells that help your blood to clot, and if you have ET, your bone marrow may be producing too many of these cells. A normal platelet count is 150 to 450 –– counts above 450 are considered higher than normal.

How can I lower my platelet count naturally?

Dark chocolate, foods with low glycemic index, garlic, ginger, omega-3 PUFA, onion, purple grape juice, tomato, and wine all reduce platelet aggregation. Dark chocolate and omega-3 PUFA also reduce P-selectin expression. In addition, dark chocolate reduces PAC-1 binding and platelet microparticle formation.

Is 400 a high platelet count?

Normal platelet counts are in the range of 150,000 to 400,000 per microliter (or 150 – 400 x 109 per liter), but the normal range for the platelet count varies slightly among different laboratories. An elevated platelet count is known as thrombocytosis.

What platelet count indicates cancer?

Thrombocytosis is defined as a platelet count greater than two standard deviations above normal, or above 400,000 per microliter in most clinical laboratories. In approaching a patient with an elevated platelet count, the clinician must first verify that the count is elevated consistently.

How high is too high for platelets?

In general, a platelet count more than 450,000 cells per microliter is considered elevated; this is known as thrombocytosis. There are numerous causes of thrombocytosis and fortunately, the majority are benign and transient.

Is 500 a high platelet count?

Recent studies have found that between 87% and 96% of people found to have platelet counts over 500,000/μl had reactive thrombocytosis. Reactive thrombocytosis is generally a self-limiting condition that resolves with the inciting condition.

Can high cholesterol cause high platelet count?

Hypercholesterolemia also increases platelet activation, likely by elevating platelet production and by direct impact on platelets. Activated platelets form PLAs, which are further increased in leukocytosis. PLA is an independent risk factor for atherothrombotic disease.

What infections cause thrombocytosis?

Among secondary, non-infectious etiologies, tissue damage was the most common, followed by malignancy and iron-deficiency anemia. The most common infectious causes of thrombocytosis were soft-tissue, pulmonary and GI infections.